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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TP53BP1 All Species: 4.55
Human Site: S860 Identified Species: 16.67
UniProt: Q12888 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12888 NP_001135451.1 1972 213574 S860 P Q T Q E K T S N S L T E D S
Chimpanzee Pan troglodytes XP_001158270 1972 213535 S860 P Q T Q E K T S N S L T E D S
Rhesus Macaque Macaca mulatta XP_001107220 1972 213653 N860 P Q T Q E K T N N L L T E D L
Dog Lupus familis XP_849774 1976 214088 H864 A E P Q E K T H N S L T K D S
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001082071 2104 231430 I965 Q E C I E K T I S V A K W S D
Zebra Danio Brachydanio rerio NP_001073639 1709 184731 V639 H S V T T D S V R N V E E E E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798355 2169 238737 E973 E I E E G K K E D A R I E E V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 97.2 89.2 N.A. N.A. N.A. N.A. N.A. N.A. 36.9 34.4 N.A. N.A. N.A. N.A. 20.5
Protein Similarity: 100 99.5 98.2 93.6 N.A. N.A. N.A. N.A. N.A. N.A. 54.5 51.3 N.A. N.A. N.A. N.A. 37.6
P-Site Identity: 100 100 80 66.6 N.A. N.A. N.A. N.A. N.A. N.A. 20 6.6 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 86.6 80 N.A. N.A. N.A. N.A. N.A. N.A. 33.3 33.3 N.A. N.A. N.A. N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 0 0 0 0 0 0 0 0 15 15 0 0 0 0 % A
% Cys: 0 0 15 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 15 0 0 15 0 0 0 0 58 15 % D
% Glu: 15 29 15 15 72 0 0 15 0 0 0 15 72 29 15 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 15 0 0 0 0 0 0 0 0 0 0 % G
% His: 15 0 0 0 0 0 0 15 0 0 0 0 0 0 0 % H
% Ile: 0 15 0 15 0 0 0 15 0 0 0 15 0 0 0 % I
% Lys: 0 0 0 0 0 86 15 0 0 0 0 15 15 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 15 58 0 0 0 15 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 15 58 15 0 0 0 0 0 % N
% Pro: 43 0 15 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 15 43 0 58 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 15 0 15 0 0 0 0 % R
% Ser: 0 15 0 0 0 0 15 29 15 43 0 0 0 15 43 % S
% Thr: 0 0 43 15 15 0 72 0 0 0 0 58 0 0 0 % T
% Val: 0 0 15 0 0 0 0 15 0 15 15 0 0 0 15 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 15 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _